Friday, April 26, 2019

Physical and Chemical Structure of Penamecillin Essay

Physical and Chemical Structure of Penamecillin - Essay modelCAS name for penamecillin is (2s, 5r, 6r)-3, hydroxymethyl (2s,5r,6r)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate , 3-dimethyl-7-oxo-6-(phenylacetyl) amino-4-thia-1-azabicyclo 3.2.0 heptane-2-carboxylic acid (acetyloxy) methyl ester. Furthermore, the CAS registry number for penamecillin is 983-85-7, and the compound InChIKey, is NLOOMWLTUVBWAW-UHFFFAOYSA-N (PubMed, ch 1).Penamecillin has a molecular weight of 406.45278 g/mol with a molecular formula of C19H22N2O6. It is a monoclinic crystalline compound (PubChem, ch 4). The compound has a density of 1.376g/cm3, a boiling point of 648.774c at 760 mmHg, with a melting point chemical chain of 105.5 c to 111 c, and a refractive index of 1.609 (Gibaldi And Schwartz, 362 ). It is moderately soluble in water but insoluble in petroleum ether. However, penamecillin is very soluble in methanol, ethanol, ethyl acetate, and benzene. It is also readily soluble in dimethylsulfoxide, chloroform, acetone, trichloromethane, and ether. Furthermore, it is an unstructured crystalline white powder with the precise optical rotation of +269 deg, at 20 deg C/D methanol. It also possesses a flash point of 346.2C, with an inflammable limit of 364C when it is a colonised powder, and 442C when it is in form of spun powder. Furthermore, it has a slight characteristic odor, and its decomposition temperature is 105 C. In equipment casualty of stability and reactivity, penamecillin is stable at ambient temperatures and should be kept away from heat or fervor sources. It is also a readily biodegradable compound even though it is not a bioaccumulation or eco-toxicity compound (PubChem, ch 4).

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